Mapping of Virginiamycin S Resistance in Bacillus Subtilis
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Molecular Biology
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Resistance to virginiamycin S (VS, a type B synergimycin) has been mapped in Bacillus subtilis. Transduction experiments with phage PBS1 indicate that the gene for virginiamycin S resistance (VSR) is cotransduced with the markers pur A16 (20%) and cys A14 (46-49%). Transformation experiments indicate that the gene for virginiamycin S resistance maps between the markers for elongation factor G and erythromycin resistance, and is therefore located within the gene cluster of ribosomal proteins.
Revised genetic linkage map of Bacillus subtilis.
Piggot P, Hoch J Microbiol Rev. 1985; 49(2):158-79.
PMID: 2989674 PMC: 373028. DOI: 10.1128/mr.49.2.158-179.1985.