Developmental Analysis of Fs(1)1867, an Egg Resorption Mutation of Drosophila Melanogaster
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The X-linked 1867+ gene seems to be a pleiotropic one. Mutation in this gene causes delay in development and abnormal bristle morphology. These phenotypes are expressed autonomously in genetic mosaics. There is no focus for the delay. The female sterility could be localized to the ovary (based on ovary transplantations). It seems that the 1867+ gene is expressed in the follicular cells at one of the last steps of oogenesis. This is suggested by the results of mosaic analysis based on mitotic recombination. Possible drawbacks of the mitotic recombination type of analyses are also discussed.
Pankotai T, Komonyi O, Bodai L, Ujfaludi Z, Muratoglu S, Ciurciu A Mol Cell Biol. 2005; 25(18):8215-27.
PMID: 16135810 PMC: 1234310. DOI: 10.1128/MCB.25.18.8215-8227.2005.