Improved Conversion of Methanol to Single-cell Protein by Methylophilus Methylotrophus

Overview

Journal Nature

Specialty Science

Date 1980 Oct 2

PMID 6776410

Citations 35

Authors

J D Windass

M J Worsey

E M Pioli

D Pioli

P T Barth

K T Atherton

E C Dart

D Byrom

K Powell

P J Senior

Affiliations

Soon will be listed here.

Abstract

The glutamate dehydrogenase gene of Escherichia coli has been cloned into broad host-range plasmids and can complement glutamate synthase mutants of Methylophilus methylotrophus. Assimilation of ammonia via glutamate dehydrogenase is more energy-efficient than via glutamate synthase, thus the recombinant organism converts more growth substrate, methanol, into cellular carbon.

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