Monoamine Oxidase Inhibitors and Histamine Metabolism

Overview

Journal Experientia

Specialty Science

Date 1980 Jul 15

PMID 6772465

Citations 2

Authors

M S Benedetti

J F Ancher

N Sontag

Affiliations

Soon will be listed here.

Abstract

In rat, histamine metabolism is altered by some nonspecific inhibitors of monoamine oxidase (MAO) such as iproniazid, and, to a lesser extent, tranylcypromine. Type A MAO inhibitors, such as clorgyline and MD780515, do not seem to interfere with the metabolism of histamine. Deprenyl, a type B MAO inhibitor, shows some inhibition which is, however, much lower than that observed with iproniazid. The strong effect of iproniazid is probably due to its DAO inhibiting properties.

Citing Articles

The Prescriber's Guide to the MAOI Diet-Thinking Through Tyramine Troubles.

Van den Eynde V, Gillman P, Blackwell B Psychopharmacol Bull. 2022; 52(2):73-116.

PMID: 35721816 PMC: 9172554.

Modification of the activity of mitochondrial monoamine oxidases in vitro and in vivo.

Baumanis E, Kalnina I, Kaminka M, Mashkovsky M, GORKIN V Agents Actions. 1981; 11(6-7):685-92.

PMID: 7340462 DOI: 10.1007/BF01978790.

References

Buffoni F . Histaminase and related amine oxidases. Pharmacol Rev. 1966; 18(4):1163-99. View

Delfosse M . [Autacoids and their antagonists (author's transl)]. J Pharm Belg. 1977; 32(3):264-303. View

Lee H, Jones R . The histamine activity of some beta-aminoethyl heterocyclic nitrogen compounds. J Pharmacol Exp Ther. 1949; 95(1):71-8. View

Imrie P, Marley E, Thomas D . Metabolism and distribution of exogenous histamine in cats. Br J Pharmacol. 1978; 64(1):109-22. PMC: 1668269. DOI: 10.1111/j.1476-5381.1978.tb08647.x. View

BURKARD W, GEY K, Pletscher A . Differentiation of monoamine oxidase and diamine oxidase. Biochem Pharmacol. 1962; 11:177-82. DOI: 10.1016/0006-2952(62)90071-0. View

Shaff R, BEAVEN M . Increased sensitivity of the enzymatic isotopic assay of histamine: measurement of histamine in plasma and serum. Anal Biochem. 1979; 94(2):425-30. DOI: 10.1016/0003-2697(79)90385-3. View

BURKARD W, GEY K, Pletscher A . Inhibition of diamine oxidase in vivo by hydrazine derivatives. Biochem Pharmacol. 1960; 3:249-55. DOI: 10.1016/0006-2952(60)90088-5. View

Suzuki O, Katsumata Y, Oya M . 1,4-Methylhistamine is a specific substrate for type B monoamine oxidase. Life Sci. 1979; 24(24):2227-30. DOI: 10.1016/0024-3205(79)90098-5. View

Waldmeier P, Feldtrauer J, Maitre L . Methylhistamine: evidence for selective deamination by MAO B in the rat brain in vivo. J Neurochem. 1977; 29(5):785-90. DOI: 10.1111/j.1471-4159.1977.tb10719.x. View

10.

URAGODA C, Kottegoda S . Adverse reactions to isoniazid on ingestion of fish with a high histamine content. Tubercle. 1977; 58(2):83-9. DOI: 10.1016/0041-3879(77)90034-4. View

11.

Kilgallon B, Shepherd D . Urinary methylhistamine as an index of histamine formation during histidine decarboxylase inhibition in the rat. Arch Int Pharmacodyn Ther. 1978; 233(2):305-13. View

12.

Thomas D, Marley E . Separation of radioactive histamine and some of its metabolites by one-dimensional paper chromatography. J Chromatogr. 1978; 148(2):477-83. DOI: 10.1016/s0021-9673(00)85308-x. View

13.

Shore P, COHN Jr V . Comparative effects of monoamine oxidase inhibitors on monoamine oxidase and diamine oxidase. Biochem Pharmacol. 1960; 5:91-5. DOI: 10.1016/0006-2952(60)90012-5. View

14.

Hough L, Domino E . Tele-methylhistamine oxidation by type B monoamine oxidase. J Pharmacol Exp Ther. 1979; 208(3):422-8. View

15.

Imrie P, Marley E, Thomas D . Metabolites of intraduodenally instilled histamine after pretreatment with monoamine oxidase inhibitors (MAOI) [proceedings]. Br J Pharmacol. 1979; 66(1):73P-74P. PMC: 2043820. View

16.

Knight R, Smith I . Metabolism in vivo and in vitro of radiolabelled histamine and telemethylhistamine in rat brain [proceedings]. Br J Pharmacol. 1978; 64(3):404P. PMC: 1668521. View

17.

URAGODA C, Lodha S . Histamine intoxication in a tuberculous patient after ingestion of cheese. Tubercle. 1979; 60(1):59-61. DOI: 10.1016/0041-3879(79)90058-8. View

18.

Shore P, BURKHALTER A, COHN Jr V . A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther. 1959; 127:182-6. View

19.

SCHAYER R . The metabolism of histamine in various species. Br J Pharmacol Chemother. 1956; 11(4):472-3. PMC: 1510572. DOI: 10.1111/j.1476-5381.1956.tb00020.x. View

20.

Reilly M, SCHAYER R . In vivo studies on histamine catabolism and its inhibition. Br J Pharmacol. 1970; 38(3):478-89. PMC: 1702573. DOI: 10.1111/j.1476-5381.1970.tb10590.x. View