Baclofen Overdose

Overview

Journal Postgrad Med J

Publisher Oxford University Press

Specialty General Medicine

Date 1980 Feb 1

PMID 6771749

Citations 11

Authors

D J Lipscomb

T J Meredith

Affiliations

Soon will be listed here.

Abstract

A 57-year-old woman suffering from multiple sclerosis took an estimated 1500 mg of baclofen. She became deeply unconscious with generalized flaccid muscle paralysis and absent tendon reflexes. Toxicological analysis confirmed the presence of baclofen together with small amounts of paracetamol and glutethimide. Supportive therapy, including assisted ventilation for 3 days, led to complete recovery; anticonvulsant drugs were necessary for the treatment of grand mal fits. The clinical features and treatment of baclofen overdose are discussed.

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References

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