The Effect of Oral Cimetidine on the Basal and Stimulated Values of Prolactin, Thyroid Stimulating Hormone, Follicle Stimulating Hormone and Luteinizing Hormone

Overview

Journal Postgrad Med J

Publisher Oxford University Press

Specialty General Medicine

Date 1980 Jan 1

PMID 6770354

Citations 2

Authors

G F Nelis

J G Van de Meene

Affiliations

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Abstract

The effect of cimetidine on the basal values of PRL, TSH, FSH and LH and on the TRH/LHRH-stimulated values of these hormones was investigated in patients with peptic ulcer. No difference was found between the values before, during or after cimetidine maintenance treatment. To evaluate whether a rise in PRL occurs during the early phase of cimetidine treatment, daily estimations were made of basal PRL values during the first week of cimetidine adminstration in volunteers. No significant difference was found. It is concluded that oral cimetidine treatment has no influence on the basal and stimulated values of PRL, TSH, FSH and LH.

Citing Articles

Comparative effect of cimetidine and ranitidine on prolactin secretion.

Nelis G, Van de Meene J Postgrad Med J. 1980; 56(657):478-80.

PMID: 6108555 PMC: 2425805. DOI: 10.1136/pgmj.56.657.478.

Adverse reactions and interactions with H2-receptor antagonists.

Penston J, Wormsley K Med Toxicol. 1986; 1(3):192-216.

PMID: 2878343 DOI: 10.1007/BF03259837.

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