» Articles » PMID: 662026

Acetylcholine Content of and Release from Isolated Pelviureteral Tract

Overview
Specialty Pharmacology
Date 1978 May 5
PMID 662026
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Measurements were taken for the acetylcholine content of animal and human pelviureteral muscle and for the release of acetylcholine at rest and during field stimulation of the isolated renal pelvis and ureter. Release was frequency-dependent, with the maximum output obtained at 10 Hz. The release of acetylcholine from reserpine-pretreated and piperoxan-treated tissues remained unchanged, but tetrodotoxin (1.10(-6) g/ml) and noradrenaline (2.10(-6) g/ml) significantly reduced the output.

Citing Articles

Functional muscarinic cholinoceptors in the isolated canine ureter.

Tomiyama Y, Wanajo I, Yamazaki Y, Murakami M, Kojima M, Shibata N Naunyn Schmiedebergs Arch Pharmacol. 2003; 367(4):348-52.

PMID: 12690426 DOI: 10.1007/s00210-003-0697-4.

References
1.
Knoll J, Vizi E . Presynaptic inhibition of acetylcholine release by endogenous and exogenous noradrenaline at high rate of stimulation. Br J Pharmacol. 1970; 40(3):554P-555P. PMC: 1703144. View

2.
Del Tacca M, Lecchini S, Stacchini B, Tonini M, Frigo G, Mazzanti L . Pharmacological studies of the rabbit and human renal pelvis. Naunyn Schmiedebergs Arch Pharmacol. 1974; 285(3):209-22. DOI: 10.1007/BF00498991. View

3.
TINDALL A . Preliminary observations on the mechanical and electrical activity of the rat ureter. J Physiol. 1972; 223(3):633-47. PMC: 1331473. DOI: 10.1113/jphysiol.1972.sp009866. View

4.
Paton W, Vizi E . The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ileum longitudinal muscle strip. Br J Pharmacol. 1969; 35(1):10-28. PMC: 1703074. DOI: 10.1111/j.1476-5381.1969.tb07964.x. View

5.
Kubacz G, CATCHPOLE B . The role of adrenergic blockade in the treatment of ureteral colic. J Urol. 1972; 107(6):949-51. DOI: 10.1016/s0022-5347(17)61178-9. View