Neuropeptide Y in the Guinea-pig Biliary Tract

Overview

Journal Experientia

Specialty Science

Date 1984 Jul 15

PMID 6547681

Citations 9

Authors

J M Allen

J Gu

T E Adrian

J M Polak

S R Bloom

Affiliations

Soon will be listed here.

Abstract

High concentrations of neuropeptide Y (NPY) have been demonstrated in the gall bladder (16.7 +/- 5.4 pmol/g), cystic duct (25.4 +/- 9.2 pmol/g) and common bile duct (54.7 +/- 11.5 pmol/g) of the guinea-pig using a recently developed radioimmunoassay. Immunoreactive NPY containing nerves were demonstrated in all layers of the biliary tree using immunocytochemistry, being particularly dense in the myenteric and mucosal plexuses.

Citing Articles

Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms.

DeMorrow S, Meng F, Venter J, Leyva-Illades D, Francis H, Frampton G Am J Physiol Gastrointest Liver Physiol. 2013; 305(3):G250-7.

PMID: 23703654 PMC: 3742859. DOI: 10.1152/ajpgi.00140.2013.

Brain-gut axis of the liver: the role of central neuropeptides.

Yoneda M, Kurosawa M, Watanobe H, Shimada T, Terano A J Gastroenterol. 2003; 37 Suppl 14:151-6.

PMID: 12572884 DOI: 10.1007/BF03326435.

Regulation of hepatic function by brain neuropeptides.

Yoneda M World J Gastroenterol. 2002; 4(3):192-196.

PMID: 11819273 PMC: 4723454. DOI: 10.3748/wjg.v4.i3.192.

Neuropeptides in pig sphincter of Oddi, bile duct, gallbladder, and duodenum.

Sand J, Tainio H, Nordback I Dig Dis Sci. 1993; 38(4):694-700.

PMID: 8462369 DOI: 10.1007/BF01316802.

Peptidergic innervation of human sphincter of Oddi.

Sand J, Tainio H, Nordback I Dig Dis Sci. 1994; 39(2):293-300.

PMID: 8313811 DOI: 10.1007/BF02090200.

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