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Platelet-derived Growth Factor Induces Rapid but Transient Expression of the C-fos Gene and Protein

Overview
Journal Nature
Specialty Science
Date 1984 Dec 20
PMID 6514007
Citations 258
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Abstract

Exposure of quiescent mouse fibroblasts to platelet-derived growth factor induces mRNA from the c-fos proto-oncogene within 10 min followed by synthesis of nuclear c-fos proteins. These are amongst the earliest described nuclear events that follow a mitogenic stimulus.

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