The Metabolism of 3H Compounds and Limits for Intakes by Workers
Overview
Nuclear Medicine
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A wide variety of 3H compounds with different physico-chemical and radiotoxic properties are produced and used throughout the world. For the purpose of worker radiation safety, 3H compounds have been divided into five classes: oxide, gaseous, insoluble, soluble organic substances and precursors of nucleic acids. Based on recent radiobiological and dosimetric data the quality factor for 3H has been suggested (QF = 2). Standards for oxide and gaseous 3H, reduced by a factor of 3-10, as compared with International Commission on Radiological Protection (ICRP) recommendations, have been suggested. New standards, 2-30 times lower than those for 3H oxide, have been worked out for the other three classes of 3H compounds. A limit for removable surface contamination from nonvolatile forms of 3H has been proposed (LSC = 1 kBq cm-2).
Cyto-Genotoxicity of Tritiated Stainless Steel and Cement Particles in Human Lung Cell Models.
Lamartiniere Y, Slomberg D, Payet M, Tassistro V, Mentana A, Baiocco G Int J Mol Sci. 2022; 23(18).
PMID: 36142309 PMC: 9499181. DOI: 10.3390/ijms231810398.