Mechanisms of Antibacterial Immunity of Mucous Membranes

Overview

Journal Folia Microbiol (Praha)

Publisher Springer

Specialty Microbiology

Date 1984 Jan 1

PMID 6500406

Citations 2

Authors

J Franek

J LIBICH

V Kubin

Affiliations

Soon will be listed here.

Abstract

A survey based on both literary data and the authors own results, concerning the mechanisms of sIgA-mediated antibacterial immunity, is presented. Secretory IgA is characterized as a specific component of the immune system of mucous membranes, which can recognize harmful bacterial and distinguish them from indigenous microflora physiologically colonizing the mucous membranes, to fix them to the mucous membrane surface and to direct further factors, such as mucin, lysozyme, etc. (which form the effector component of the mucous membrane immunity system) for their final inactivation and neutralization.

Citing Articles

Antibacterial immunity of lower airways: local or localized?.

Franek J, LIBICH J, Malina J Folia Microbiol (Praha). 1985; 30(3):247-57.

PMID: 3891551 DOI: 10.1007/BF02923517.

Intestinal mucus gel and secretory antibody are barriers to Campylobacter jejuni adherence to INT 407 cells.

McSweegan E, Burr D, Walker R Infect Immun. 1987; 55(6):1431-5.

PMID: 3570473 PMC: 260532. DOI: 10.1128/iai.55.6.1431-1435.1987.

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