DNA Sequence Encoding the NH2-terminal Peptide Involved in Transport of Lambda Receptor, an Escherichia Coli Secretory Protein

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1980 May 1

PMID 6446717

Citations 19

Authors

J Hedgpeth

J M CLEMENT

C Marchal

D Perrin

M Hofnung

Affiliations

Soon will be listed here.

Abstract

lamB encodes the lambda receptor of Escherichia coli, an outer membrane protein. We have identified the beginning of the lamB gene by correlating DNA nucleotide sequence with a partial sequence of the primary translation product of lamB. We show that lambda receptor is synthesized as a precursor containing an extra 25 amino acids at its NH2 terminus. These amino acids are predominately hydrophobic and probably comprise a structure required for initiation of transport of lambda receptor from the cytoplasm to the outer membrane.

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