Niacin, Nitrate and Pyrazinamide Studies Using Middlebrook 7H10 Broth

Overview

Journal Eur J Clin Microbiol

Specialty Microbiology

Date 1984 Dec 1

PMID 6441710

Citations 1

Authors

J J Damato

M T Collins

J K McClatchy

Affiliations

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Abstract

An innovative and rapid method for testing mycobacteria was developed using Middlebrook 7H10 Tween Broth in place of conventional media. Niacin production, nitrate reduction and the breakdown of pyrazinamidase were determined in 198 mycobacteria isolates. Less than nine days were required to obtain positive test results, and the correlation of tween broth with conventional test methods exceeded 98%.

Citing Articles

Purification, gene cloning, targeted knockout, overexpression, and biochemical characterization of the major pyrazinamidase from Mycobacterium smegmatis.

Boshoff H, Mizrahi V J Bacteriol. 1998; 180(22):5809-14.

PMID: 9811635 PMC: 107651. DOI: 10.1128/JB.180.22.5809-5814.1998.

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