In Vitro Effect of the Slime of Pseudomonas Aeruginosa on the Function of Human Polymorphonuclear Neutrophils

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1984 Jun 1

PMID 6427114

Citations 6

Authors

P F Laharrague

J X Corberand

G Fillola

B J Gleizes

A M Fontanilles

E GYRARD

Affiliations

Soon will be listed here.

Abstract

The slime of Pseudomonas aeruginosa markedly impaired the in vitro motility, endocytosis, and phagosome formation of normal human polymorphonuclear neutrophils. This profound impairment of neutrophils, although without alteration of their viability, may contribute to the virulence of this microorganism.

Citing Articles

Association of slime with pathogenicity of coagulase-negative staphylococci causing nosocomial septicemia.

Ishak M, Groschel D, Mandell G, Wenzel R J Clin Microbiol. 1985; 22(6):1025-9.

PMID: 4066912 PMC: 271871. DOI: 10.1128/jcm.22.6.1025-1029.1985.

[Infections of the respiratory tract with Pseudomonas aeruginosa in cystic fibrosis].

Winkler U, Wingender J, Jager K Klin Wochenschr. 1985; 63(11):490-8.

PMID: 3925219 DOI: 10.1007/BF01747978.

Decreased delayed-type hypersensitivity and increased protection to Listeria monocytogenes seen in mice infected with mucoid and nonmucoid Pseudomonas aeruginosa.

Blackwood L Infect Immun. 1985; 47(3):840-2.

PMID: 3918939 PMC: 261406. DOI: 10.1128/iai.47.3.840-842.1985.

Unusual mechanism of pathogenicity of Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

Tummler B Infection. 1987; 15(4):311-2.

PMID: 3117705 DOI: 10.1007/BF01644144.

Histamine release from basophils in cystic fibrosis.

SCHONFELD W, Saak A, Steinkamp G, Van der Hardt H, Konig W Clin Exp Immunol. 1989; 76(3):434-9.

PMID: 2473860 PMC: 1541905.

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