The Stacking Interactions in 7-methylguanine-tryptophan Systems, a Model Study for the Interaction Between the 'cap' Structure of MRNA and Its Binding Protein
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Stacking interactions were shown by spectroscopic and X-ray crystallographic studies to be formed between the tryptophan and the protonated 7-methylguanine derivatives. These interactions would be in part responsible for the specific interaction between the 5'-terminal capped structure of mRNA and its binding protein.
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Tsotsoros S, Lutz P, Daniel A, Peterson E, de Paiva R, Rivera E Chem Sci. 2017; 8(2):1269-1281.
PMID: 28451269 PMC: 5369524. DOI: 10.1039/c6sc03445d.
Structural and functional insights into Mimivirus ORFans.
Saini H, Fischer D BMC Genomics. 2007; 8:115.
PMID: 17490476 PMC: 1876218. DOI: 10.1186/1471-2164-8-115.
Genetically engineered live attenuated influenza A virus vaccine candidates.
Parkin N, Chiu P, Coelingh K J Virol. 1997; 71(4):2772-8.
PMID: 9060631 PMC: 191400. DOI: 10.1128/JVI.71.4.2772-2778.1997.
Altmann M, Handschin C, Trachsel H Mol Cell Biol. 1987; 7(3):998-1003.
PMID: 3550438 PMC: 365169. DOI: 10.1128/mcb.7.3.998-1003.1987.
Amino acid sequence of the mRNA cap-binding protein from human tissues.
Rychlik W, Domier L, Gardner P, Hellmann G, Rhoads R Proc Natl Acad Sci U S A. 1987; 84(4):945-9.
PMID: 3469651 PMC: 304336. DOI: 10.1073/pnas.84.4.945.