Crescentic Light-chain Glomerulopathy. Report of a Case

Overview

Journal Arch Pathol Lab Med

Specialty Pathology

Date 1983 Jun 1

PMID 6405721

Citations 4

Authors

D J Lapenas

S J Drewry

R L Luke 3rd

D A Leeber

Affiliations

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Abstract

Light-chain glomerulopathy occurred in a middle-aged woman with adult-onset diabetes mellitus and IgG-kappa light-chain multiple myeloma. Unusual features of the glomerulopathy included the presence of numerous epithelial crescents and rapid progression to chronic renal failure. The aggressiveness of her disease may be related to her underlying diabetes mellitus and associated abnormalities in glomerular clearance of macromolecules, including immunoglobulin light chains.

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Light chain deposition disease of the kidney. Morphological aspects in 24 patients.

Strom E, Fogazzi G, Banfi G, Pozzi C, Mihatsch M Virchows Arch. 1994; 425(3):271-80.

PMID: 7812513 DOI: 10.1007/BF00196150.

Epithelial crescent in diabetic glomeruli. A case report.

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Renal and systemic kappa light chain deposits and their plasma cell origin identified by immunoelectron microscopy.

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