Cutaneous Metastasis of a Radiation-associated Thyroid Medullary Carcinoma

Overview

Journal J Endocrinol Invest

Publisher Springer

Specialty Endocrinology

Date 1984 Dec 1

PMID 6397504

Citations 1

Authors

G Bevilacqua

S Mariotti

M Castagna

C Marcocci

G C Di Coscio

E Martino

Affiliations

Soon will be listed here.

Abstract

The rare event of a single cutaneous metastasis occurred in a 37-year-old white man two years after a subtotal thyroidectomy for sporadic medullary carcinoma is reported. The endocrine nature of the tumor is revealed by the ultrastructural study, and the type of secretion by the biochemical assay of calcitonin (CT) in the serum and in the tumor tissue extract and by the PAP (peroxidase-anti-peroxidase) technique with anti-CT antibodies on paraffin sections. The cytological and histological findings are described. Some peculiar ultrastructural aspects are presented in details. The fact that the patient received a course of Rx therapy (3,000 rads) on the neck for cervical syringomyelia at the age of 20 years is stressed.

Citing Articles

Radiation port cutaneous metastases: reports of two patients whose recurrent visceral cancers presented as skin lesions at the site of previous radiation and literature review.

Hoyt B, Cohen P Indian J Dermatol. 2014; 59(2):176-81.

PMID: 24700938 PMC: 3969679. DOI: 10.4103/0019-5154.127680.

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