Analysis of an Inhibin Preparation Reveals Apparent Identity Between a Peptide with Inhibin-like Activity and a Sperm-coating Antigen

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1984 Oct 15

PMID 6386522

Citations 7

Authors

J Johansson

A Sheth

E Cederlund

H Jornvall

Affiliations

Soon will be listed here.

Abstract

The amino acid sequence of a large form of inhibin-like peptide in human seminal plasma was determined, and compared with structures reported for similar inhibin preparations and a seminal plasma globulin. The data confirm and correlate previous reports on this form of inhibin-like peptide. The structural comparisons further suggest that the peptide is closely similar to or possibly identical to a sperm-coating antigen reported to be synthesized from prostatic epithelium. This may correlate with non-gonadal origins of inhibin-like material and will help to elucidate the biological roles of inhibin(s).

Citing Articles

Immunoreactive inhibin-like material in serum and gastric juice of patients with benign and malignant diseases of the stomach.

Shanbhag S, SHETH A, Nanivadekar S, SHETH N Br J Cancer. 1985; 51(6):877-82.

PMID: 4005143 PMC: 1977073. DOI: 10.1038/bjc.1985.133.

Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.

Forage R, Ring J, Brown R, McInerney B, Cobon G, Gregson R Proc Natl Acad Sci U S A. 1986; 83(10):3091-5.

PMID: 3458167 PMC: 323458. DOI: 10.1073/pnas.83.10.3091.

Synthetic human seminal alpha-inhibin-92 selectively suppresses follicle-stimulating hormone release in vivo.

Yu W, McCANN S, Li C Proc Natl Acad Sci U S A. 1988; 85(1):289-92.

PMID: 3124100 PMC: 279530. DOI: 10.1073/pnas.85.1.289.

Fish skeletal muscle contains a novel serine proteinase with an unusual subunit composition.

Folco E, Busconi L, Martone C, Sanchez J Biochem J. 1989; 263(2):471-5.

PMID: 2597118 PMC: 1133452. DOI: 10.1042/bj2630471.

Studies on immunocytochemical localization of inhibin-like material in human prostatic tissue: comparison of its distribution in normal, benign and malignant prostates.

Doctor V, SHETH A, Simha M, Arbatti N, Aaveri J, SHETH N Br J Cancer. 1986; 53(4):547-54.

PMID: 2423106 PMC: 2001445. DOI: 10.1038/bjc.1986.85.