Abdominal Pain Associated with IgA Nephropathy. Possible Mechanism
Overview
Affiliations
A 36-year-old man presented with IgA nephropathy (Berger's disease) and acute abdominal pain. Surgical biopsy of the ileum revealed deposits of IgA, C3, and fibrin in segments of the wall of submucosal arteries. The immune deposits appeared associated with areas of fibrinoid necrosis. These findings support the hypothesis that Berger's disease is a systemic disease, and provide a possible explanation for the abdominal pain associated with IgA nephropathy.
Arachidonic acid metabolism as a therapeutic target in AKI-to-CKD transition.
Li X, Suo P, Wang Y, Zou L, Nie X, Zhao Y Front Pharmacol. 2024; 15:1365802.
PMID: 38523633 PMC: 10957658. DOI: 10.3389/fphar.2024.1365802.
Yang T, Du Y Am J Hypertens. 2012; 25(10):1042-9.
PMID: 22695507 PMC: 3578476. DOI: 10.1038/ajh.2012.67.
Immunoglobulin A enteropathy: a possible variant of Henoch-Schönlein purpura.
Kato S, Ozawa K, Ando N, Naganuma H, Iinuma K, Nagura H Dig Dis Sci. 2005; 49(11-12):1777-81.
PMID: 15628702 DOI: 10.1007/s10620-004-9569-0.