Calcitonin-mediated Changes in Plasma Tryptophan and Brain 5-hydroxytryptamine and Acetylcholinesterase Activity in Rats

Overview

Journal Biochem J

Specialty Biochemistry

Date 1978 Feb 15

PMID 637854

Citations 11

Authors

A M Nakhla

A P Nandi Majumdar

Affiliations

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Abstract

After a single injection of calcitonin (20 M.R.C. units/kg body wt.) marked decreases in both Ca2+ and free tryptophan in plasma were observed, during the initial period of the treatment (up to 1 h). However, 5-hydrotryptamine contents of the whole brain and the cerebral acetylcholinesterase activity were greatly enhanced. The cerebellar acetylcholinesterase activity was not influenced by calcitonin.

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