Isolate-specific S-antigen of Plasmodium Falciparum Contains a Repeated Sequence of Eleven Amino Acids

Overview

Journal Nature

Specialty Science

Date 1983 Dec 22

PMID 6361573

Citations 47

Authors

R L Coppel

A F Cowman

K R Lingelbach

G V Brown

R B Saint

D J Kemp

R F Anders

Affiliations

Soon will be listed here.

Abstract

Antibodies raised against a Plasmodium falciparum protein expressed in Escherichia coli reacted with a 220,000-molecular weight antigen of mature blood-stage parasites. The protein resembles the sporozoite surface antigen being composed of tandem repeats of 11 amino acids. However, it is isolate-specific and the encoding gene is not detectable in strains that do not express the protein.

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