Stimulation of Intestinal Chromatin Template Activity by Dietary Carbohydrates in Adult Rats
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Oral administration of a 70% solution of sucrose to starved adult rats resulted 1 h after feeding in a 3.5-fold stimulation of intestinal chromatin template activity assayed in vitro using E. coli RNA polymerase. A similar stimulatory effect was observed with fructose, whereas glucose exhibited a weaker effect, indicating that the nature of the ingested carbohydrate may have a direct effect on the extent of intestinal chromatin template activation.
Dietary sugar promotes gene activation in intestinal cell chromatin of adult rats.
Raul F, von der Decken A Experientia. 1984; 40(4):364-5.
PMID: 6201386 DOI: 10.1007/BF01952554.