A Conserved DNA Sequence in Homoeotic Genes of the Drosophila Antennapedia and Bithorax Complexes

Overview

Journal Nature

Specialty Science

Date 1984 Mar 4

PMID 6323992

Citations 271

Authors

W McGinnis

M S Levine

E Hafen

A Kuroiwa

W J Gehring

Affiliations

Soon will be listed here.

Abstract

A repetitive DNA sequence has been identified in the Drosophila melanogaster genome that appears to be localized specifically within genes of the bithorax and Antennapedia complexes that are required for correct segmental development. Initially identified in cloned copies of the genes Antennapedia, Ultrabithorax and fushi tarazu, the sequence is also contained within two other DNA clones that have characteristics strongly suggesting that they derive from other homoeotic genes.

Citing Articles

Genome-wide identification and expression profile analysis of TALE superfamily genes under hormone and abiotic stress in maize ( L.).

Guan P, Zhao D, Wei L, Cui P, Zhang S Front Plant Sci. 2025; 16:1489177.

PMID: 40061035 PMC: 11885238. DOI: 10.3389/fpls.2025.1489177.

On the prospects of basal cognition research becoming fully evolutionary: promising avenues and cautionary notes.

Fabregas-Tejeda A, Sims M Hist Philos Life Sci. 2025; 47(1):10.

PMID: 39913055 PMC: 11802611. DOI: 10.1007/s40656-025-00660-y.

The impact of retrotransposons on zygotic genome activation and the chromatin landscape of early embryos.

Solberg T, Kobayashi-Ishihara M, Siomi H Ann N Y Acad Sci. 2024; 1542(1):11-24.

PMID: 39576233 PMC: 11668504. DOI: 10.1111/nyas.15260.

A conserved sequence that sparked the field of evo-devo.

Pick L, Au K Dev Biol. 2024; 518():1-7.

PMID: 39550026 PMC: 11703672. DOI: 10.1016/j.ydbio.2024.11.005.

"The Logic of Monsters:" Pere Alberch and the Evolutionary Significance of Experimental Teratology.

Sanchez Arteaga J J Hist Biol. 2024; 57(3):379-401.

PMID: 39212877 PMC: 11438615. DOI: 10.1007/s10739-024-09783-7.