Molecular Epidemiology of Human Rotaviruses. Analysis of Outbreaks of Acute Gastroenteritis in Glasgow and the West of Scotland 1981/82 and 1982/83

Overview

Journal J Hyg (Lond)

Publisher Cambridge University Press

Specialty Public Health

Date 1984 Apr 1

PMID 6323577

Citations 25

Authors

E A Follett

R C Sanders

G M Beards

F Hundley

U Desselberger

Affiliations

Soon will be listed here.

Abstract

The molecular epidemiology of rotavirus infections in Glasgow and the west of Scotland during 1981/82 and 1982/83 was investigated by electron microscopy, ELISA testing and RNA migration pattern analysis. In 1981/82, rotaviruses of both the 'long' and the 'short' electropherotype (in different variants) co-circulated from the onset throughout the winter peak of the outbreak. Approximately 80% of the children were infected during the first year of life. No differences in incidence were found between sexes. In 1982/83 the isolated rotaviruses were almost exclusively of the 'long' electropherotype (in different variants) and 36% of the children were infected beyond the first year of life. Rotaviruses of the 'long' electropherotype serologically were of subgroup II and serotype 1 and those of the 'short' electropherotype of subgroup I and serotype 2.

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