Antiviral Activity Released from Aedes Albopictus Cells Persistently Infected with Semliki Forest Virus
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Aedes albopictus (mosquito) cells persistently infected with Semliki Forest virus released an agent which inhibited virus production by A. albopictus cells infected with homologous virus. Inhibition of virus production was accompanied by a marked reduction in the synthesis of viral RNA and viral proteins. Expression of the antiviral effect was prevented by pretreatment of cells with actinomycin. No analogous antiviral activity was detected in culture fluids of A. albopictus cells persistently infected with a flavivirus (Kunjin virus) or a bunyavirus (Bunyamwera virus).
Characterization of Viral Interference in C6/36 Cells Persistently Infected with Dengue Virus 2.
Gonzalez-Flores A, Salas-Benito M, Rosales-Garcia V, Zarate-Segura P, Del Angel R, De Nova-Ocampo M Pathogens. 2023; 12(9).
PMID: 37764943 PMC: 10536104. DOI: 10.3390/pathogens12091135.
Response to Dengue virus infections altered by cytokine-like substances from mosquito cell cultures.
Kanthong N, Laosutthipong C, Flegel T BMC Microbiol. 2010; 10:290.
PMID: 21078201 PMC: 2995469. DOI: 10.1186/1471-2180-10-290.
Kuno G, Chang G Clin Microbiol Rev. 2005; 18(4):608-37.
PMID: 16223950 PMC: 1265912. DOI: 10.1128/CMR.18.4.608-637.2005.
The alphaviruses: gene expression, replication, and evolution.
Strauss J, Strauss E Microbiol Rev. 1994; 58(3):491-562.
PMID: 7968923 PMC: 372977. DOI: 10.1128/mr.58.3.491-562.1994.
Condreay L, Brown D J Virol. 1986; 58(1):81-6.
PMID: 3951024 PMC: 252879. DOI: 10.1128/JVI.58.1.81-86.1986.