Myelination in Rabbit Optic Nerves is Accelerated by Artificial Eye Opening

Overview

Journal Neurosci Lett

Specialty Neurology

Date 1980 Mar 1

PMID 6302574

Citations 34

Authors

H Tauber

T V Waehneldt

V Neuhoff

Affiliations

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Abstract

Artificial opening of the eyes of young rabbits on the 5th postnatal day led to accelerated myelination: the myelin-specific basic and proteolipid proteins nearly doubled between the 7th and the 10th postnatal days when compared to controls; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) activity also increased by about 60%. Conversely, lowered AChE activities presumably reflected elevated myelin/axolemma ratios. Myelination in treated animals normalized during later ontogenetic stages (greater than 20th postnatal day).

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