Primary Structure of the Lambda Repressor

Overview

Journal Biochemistry

Specialty Biochemistry

Date 1978 Mar 21

PMID 629949

Citations 37

Authors

R T Sauer

R Anderegg

Affiliations

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Abstract

The complete covalent structure of the bacteriophage lambda repressor has been determined by sequential Edman degradation, gas chromatographic-mass spectrometric peptide sequencing, and DNA sequencing of the repressor gene cI. The repressor is a single-chain, acidic protein containing 236 amino acids. The amino terminal 40 residues are highly polar and basic. Lysines and arginines in the sequence tend to be clustered.

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