Comparison of the Amino Acid Sequence of the Major Immunogen from Three Serotypes of Foot and Mouth Disease Virus

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1982 Dec 20

PMID 6298715

Citations 27

Authors

A J Makoff

C A Paynter

D J Rowlands

J C Boothroyd

Affiliations

Soon will be listed here.

Abstract

Cloned cDNA molecules from three serotypes of FMDV have been sequenced around the VP1-coding region. The predicted amino acid sequences for VP1 were compared with the published sequences and variable regions identified. The amino acid sequences were also analysed for hydrophilic regions. Two of the variable regions, numbered 129-160 and 193-204 overlapped hydrophilic regions, and were therefore identified as potentially immunogenic. These regions overlap regions shown by others to be immunogenic.

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