[Plasma Digoxin Concentration in Different Age Groups (author's Transl)]

Overview

Journal Klin Wochenschr

Specialty General Medicine

Date 1978 Jan 15

PMID 628195

Citations 2

Authors

D Lang

R Hofstetter

G von Bernuth

Affiliations

Soon will be listed here.

Abstract

Plasma digoxin concentration during maintenance therapy with digoxin was determined in premature and mature newborns, infants, children and adults. The plasma digoxin concentration of newborns was significantly higher than in adults; in addition, in the group of premature newborns it also was higher than in infants and children. These differences in plasma digoxin concentrations may be explained by differences in dose, volume of distribution and excretion rate of digoxin in the various age groups.

Citing Articles

Pharmacokinetics and dosagae of digoxin in neonates and infants.

Nyberg L, Wettrell G Eur J Clin Pharmacol. 1980; 18(1):69-74.

PMID: 7398751 DOI: 10.1007/BF00561481.

Postmortem tissue and plasma concentrations of digoxin in newborns and infants.

Lang D, Hofstetter R, von Bernuth G Eur J Pediatr. 1978; 128(3):151-61.

PMID: 668723 DOI: 10.1007/BF00444300.

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