Pacifico S, Carotenuto A, Brancaccio D, Novellino E, Marzola E, Ferrari F
Sci Rep. 2017; 7:45817.
PMID: 28383520
PMC: 5382891.
DOI: 10.1038/srep45817.
Dyniewicz J, Lipinski P, Kosson P, Lesniak A, Bochynska-Czyz M, Muchowska A
ACS Med Chem Lett. 2017; 8(1):73-77.
PMID: 28105278
PMC: 5238479.
DOI: 10.1021/acsmedchemlett.6b00381.
Franco R, Martinez-Pinilla E, Lanciego J, Navarro G
Front Pharmacol. 2016; 7:76.
PMID: 27065866
PMC: 4815248.
DOI: 10.3389/fphar.2016.00076.
Lee C, Ho I
Cells. 2014; 2(4):689-714.
PMID: 24709876
PMC: 3972655.
DOI: 10.3390/cells2040689.
Wu J, An G, Lin S, Xie J, Zhou W, Sun H
Chem Commun (Camb). 2013; 50(10):1259-61.
PMID: 24336500
PMC: 3929111.
DOI: 10.1039/c3cc48509a.
Biological active analogues of the opioid peptide biphalin: mixed α/β(3)-peptides.
Mollica A, Pinnen F, Costante R, Locatelli M, Stefanucci A, Pieretti S
J Med Chem. 2013; 56(8):3419-23.
PMID: 23547584
PMC: 3942533.
DOI: 10.1021/jm301456c.
A molecular dynamics study on opioid activities of biphalin molecule.
Hsieh J, Chiang T, Chen J, Chen Y, Lin H, Hwang C
J Mol Model. 2010; 17(10):2455-64.
PMID: 21181216
DOI: 10.1007/s00894-010-0931-1.
New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4' positions and non-hydrazine linkers.
Mollica A, Pinnen F, Feliciani F, Stefanucci A, Lucente G, Davis P
Amino Acids. 2010; 40(5):1503-11.
PMID: 20924622
PMC: 5689474.
DOI: 10.1007/s00726-010-0760-7.
A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic.
Salvadori S, Trapella C, Fiorini S, Negri L, Lattanzi R, Bryant S
Bioorg Med Chem. 2007; 15(22):6876-81.
PMID: 17851080
PMC: 2084217.
DOI: 10.1016/j.bmc.2007.08.047.
Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.
Lee Y, Agnes R, Badghisi H, Davis P, Ma S, Lai J
J Med Chem. 2006; 49(5):1773-80.
PMID: 16509592
PMC: 1614704.
DOI: 10.1021/jm050851n.
Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series.
Daniels D, Lenard N, Etienne C, Law P, Roerig S, Portoghese P
Proc Natl Acad Sci U S A. 2005; 102(52):19208-13.
PMID: 16365317
PMC: 1323165.
DOI: 10.1073/pnas.0506627102.
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
Mosberg H, Hurst R, Hruby V, Gee K, Yamamura H, Galligan J
Proc Natl Acad Sci U S A. 1983; 80(19):5871-4.
PMID: 6310598
PMC: 390177.
DOI: 10.1073/pnas.80.19.5871.
Selectivities of opioid peptide analogues as agonists and antagonists at the delta-receptor.
Corbett A, Gillan M, KOSTERLITZ H, McKnight A, Paterson S, Robson L
Br J Pharmacol. 1984; 83(1):271-9.
PMID: 6091824
PMC: 1987170.
DOI: 10.1111/j.1476-5381.1984.tb10143.x.
The effects of long-term treatment of NG108-15 cells with penta- and tetrapeptide enkephalin dimers on opioid receptor binding and cyclic AMP (cAMP) levels.
Krumins S
Cell Mol Neurobiol. 1987; 7(2):221-8.
PMID: 2820579
PMC: 11567633.
DOI: 10.1007/BF00711556.
Enkephalinergic inhibition in parasympathetic ganglia of the urinary bladder of the cat.
de Groat W, Kawatani M
J Physiol. 1989; 413:13-29.
PMID: 2600844
PMC: 1189086.
DOI: 10.1113/jphysiol.1989.sp017639.