In Vitro Infection of Murine Macrophages with Junin Virus

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1982 Jan 1

PMID 6274800

Citations 6

Authors

P H Gonzalez

J S Lampuri

C E Coto

R P Laguens

Affiliations

Soon will be listed here.

Abstract

Mouse peritoneal macrophages were successfully infected with two strains of Junin virus producing high titers with no apparent cell damage. Infected cultures survived longer than noninfected cultures. The pattern of virus release suggested a persistent infection. Virus replication was delayed in macrophages from mice previously immunized with Junin virus. These results support the opinion that macrophages are targets for virus replication in vivo infections.

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Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages.

Groseth A, Hoenen T, Weber M, Wolff S, Herwig A, Kaufmann A PLoS Negl Trop Dis. 2011; 5(5):e1137.

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References

Schwartz R, Lohler J, Lehmann-Grube F . Infection of cultivated mouse peritoneal macrophages with lymphocytic choriomeningitis virus. J Gen Virol. 1978; 39(3):565-70. DOI: 10.1099/0022-1317-39-3-565. View

Doyle M, Oldstone M . Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections. J Immunol. 1978; 121(4):1262-9. View

Popescu M, Lohler J, Lehmann-Grube F . Infectious lymphocytes in lymphocytic choriomeningitis virus carrier mice. J Gen Virol. 1979; 42(3):481-92. DOI: 10.1099/0022-1317-42-3-481. View

Carballal G, Cossio P, Laguens R, Ponzinibbio C, Oubina J, Meckert P . Junin virus infection of guinea pigs: immunohistochemical and ultrastructural studies of hemopoietic tissue. J Infect Dis. 1981; 143(1):7-14. DOI: 10.1093/infdis/143.1.7. View

Coto C, Damonte E, Catello M, Weissenbacher M . Protection of guinea pigs inoculated with Tacaribe virus against lethal doses of Junin virus. J Infect Dis. 1980; 141(3):389-93. DOI: 10.1093/infdis/141.3.389. View