Immunofluorescent Detection of Hormone Receptors in Cutaneous Melanocytic Tumours

Overview

Journal Br J Cancer

Specialty Oncology

Date 1981 May 1

PMID 6264940

Citations 1

Authors

A J Thompson

M G Cook

P G Gill

Affiliations

Soon will be listed here.

Abstract

Immunofluorescent assessment of hormone receptors in melanocytic tumours is quite feasible without loss of diagnostic material, in contrast to the impracticability of quantitative biochemical assays. Using this method, oestrogen receptors were demonstrated in 4/6, and progesterone receptors in 3/5 patients with metastatic melanoma. Receptors were not found in 3 patients with primary cutaneous melanomas of the superficial spreading type. Progesterone receptors were present in the junctional component of a naevus from one healthy person.

Citing Articles

Immunohistologic and histochemical methods for detection of steroid binding in breast cancer: a reappraisal.

PERTSCHUK L, Tobin E, Carter A, Eisenberg K, Leo V, Gaetjens E Breast Cancer Res Treat. 1981; 1(4):297-314.

PMID: 6756510 DOI: 10.1007/BF01806746.

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