Environmental Factors Altering Thyroid Function and Their Assessment

Overview

Journal Environ Health Perspect

Date 1981 Apr 1

PMID 6263611

Citations 5

Authors

C P Barsano

Affiliations

Soon will be listed here.

Abstract

Chronic ingestion of modest doses of dietary iodine, radiation, and polyhalogenated biphenyls (PCB's and PBB's) are environmental factors with known or suspected adverse effects on the human thyroid. Iodine consumption in the United States is approaching 1 mg daily for a large segment of the population. Data are reviewed which support the need for concern regarding the long-term adverse effects of dietary iodine on thyroid function, particularly in certain susceptible individuals. Environmental sources of radiation pose a significant risk of thyroid cancer and hypothyroidism under certain circumstances which may be intentional, inadvertent, or accidental. Exposure to polyhalogenated biphenyls during manufacture or as industrial pollutants are hazardous to man and to wildlife in moderate or large quantities and perhaps also in small amounts. The need to investigate the potential harm posed by these factors in the quantities commonly encountered is emphasized.

Citing Articles

Persistent organic pollutants and anti-thyroid peroxidase levels in Akwesasne Mohawk young adults.

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Polychlorinated biphenyls (Aroclor 1254) do not uniformly produce agonist actions on thyroid hormone responses in the developing rat brain.

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Goitre and wasting induced in hamsters by hexachlorobenzene.

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Target organ defects in thyroid autoimmune disease.

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Enhanced thyroxine metabolism in hexachlorobenzene-intoxicated rats.

Kleiman de Pisarev D, Sancovich H, Ferramola de Sancovich A J Endocrinol Invest. 1989; 12(11):767-72.

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