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Histone 2B Can Be Modified by the Attachment of Ubiquitin

Overview
Journal Nucleic Acids Res
Publisher Oxford University Press
Specialty Biochemistry
Date 1980 Oct 24
PMID 6255427
Citations 90
Authors
M H West
W M Bonner
Affiliations
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Abstract

Histone 2B in mouse and man can be modified by the post-translational addition of ubiquitin. In mouse L1210 cells, both H2B variants are modified, however only to the extent of 1-1.5% compared with about 11% of H2A. Analysis of cyanogen bromide peptides shows that ubiquitin is attached to the C-terminal part of the histone.

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