Curing of a Plasmid is Correlated with an Attenuation of Virulence in the Marine Fish Pathogen Vibrio Anguillarum

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1980 Mar 1

PMID 6247282

Citations 58

Authors

J H Crosa

L L Hodges

M H Schiewe

Affiliations

Soon will be listed here.

Abstract

The transposon A sequence Tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen Vibrio anguillarum. Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.

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