The Lambda Phage Att Site: Functional Limits and Interaction with Int Protein

Overview

Journal Nature

Specialty Science

Date 1980 May 8

PMID 6246439

Citations 55

Authors

P L Hsu

W Ross

A Landy

Affiliations

Soon will be listed here.

Abstract

Site specific integrative recombination of bacteriophage lambda involves unequal partners. The minimal phage att site is composed of approximately 240-base pairs and four distinct binding sites for Int protein, at least three of which are crucial for function. This 'donor site' recombines efficiently with a smaller 'recipient site' that lacks the extensive interactions with Int protein.

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