The Activity of Ciprofloxacin and Other 4-quinolones Against Chlamydia Trachomatis and Mycoplasmas in Vitro

Overview

Journal Eur J Clin Microbiol

Specialty Microbiology

Date 1984 Aug 1

PMID 6237903

Citations 33

Authors

G L Ridgway

G Mumtaz

F G Gabriel

J D Oriel

Affiliations

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Abstract

Ciprofloxacin was found to be the most active of a group of 4-quinolone antibiotics tested against the SA2f strain of Chlamydia trachomatis (MBC and MIC 1.0 mg/l). Against genital isolates of Chlamydia trachomatis, ciprofloxacin was twice as active as rosoxacin. Ciprofloxacin showed similar activity to that of oxytetracycline against clinical isolates of Mycoplasma hominis and Ureaplasma urealyticum, and was 8-fold more active than rosoxacin against the latter.

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References

Ridgway G, Owen J, Oriel J . A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system. J Antimicrob Chemother. 1976; 2(1):71-6. DOI: 10.1093/jac/2.1.71. View

Ridgway G, Owen J, Oriel J . The antimicrobial susceptibility of Chlamydia trachomatis in cell culture. Br J Vener Dis. 1978; 54(2):103-6. PMC: 1046370. DOI: 10.1136/sti.54.2.103. View

Evans R, Taylor-Robinson D . The incidence of tetracycline-resistant strains of Ureaplasma urealyticum. J Antimicrob Chemother. 1978; 4(1):57-63. DOI: 10.1093/jac/4.1.57. View

Eandi M, Viano I, DI NOLA F, Leone L, GENAZZANI E . Pharmacokinetics of norfloxacin in healthy volunteers and patients with renal and hepatic damage. Eur J Clin Microbiol. 1983; 2(3):253-9. DOI: 10.1007/BF02029528. View

Meier-Ewert H, Weil G, Millott G . In vitro activity of norfloxacin against Chlamydia trachomatis. Eur J Clin Microbiol. 1983; 2(3):271-2. DOI: 10.1007/BF02029532. View