Association Between Phosphoglucomutase (PGM1) and Group-specific Component (Gc) Subtypes and Tuberculosis

Overview

Journal J Med Genet

Specialty Genetics

Date 1983 Jun 1

PMID 6224013

Citations 2

Authors

S S Papiha

S S Agarwal

I White

Affiliations

Soon will be listed here.

Abstract

The polymorphism of PGM1 and Gc was studied by isoelectric focusing in pulmonary tuberculosis patients and controls. For the Gc system, the phenotypic frequencies did not differ significantly, but the PGM1 system showed a significant difference in the tuberculosis patients compared to controls. The data presented here show the potential of newly developed techniques to distinguish subjects with susceptibility to disease.

Citing Articles

Association between Gc genotype and susceptibility to TB is dependent on vitamin D status.

Martineau A, Leandro A, Anderson S, Newton S, Wilkinson K, Nicol M Eur Respir J. 2009; 35(5):1106-12.

PMID: 19797128 PMC: 2864196. DOI: 10.1183/09031936.00087009.

An association between Gc (vitamin D-binding protein) alleles and susceptibility to rheumatic fever.

Bahr G, Eales L, Nye K, Majeed H, Yousof A, Behbehani K Immunology. 1989; 67(1):126-8.

PMID: 2737695 PMC: 1385300.

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