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The Ratio Between Intrinsic 115 KDa and 30 KDa Peptides As a Marker of Fibre Type-specific Sarcoplasmic Reticulum in Mammalian Muscles

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Journal FEBS Lett
Specialty Biochemistry
Date 1983 Jul 25
PMID 6223839
Citations 7
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Abstract

Sarcoplasmic reticulum displays characteristic differences in Ca2+-uptake, Ca2+-ATPase and the pattern of membrane proteins in type I, IIA and IIB fibres. The ratio between the 115 kDa Ca2+-ATPase and a 30 kDa protein is of characteristic magnitude in the sarcoplasmic reticulum of the three fibre types in rat muscles. The slow-to-fast fibre type transformation observed in rabbits during chronic nerve stimulation is accompanied by predictable changes of this ratio.

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