Sequential Utilization of Mixed Monosaccharides by Yeasts

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 1982 Apr 1

PMID 6211144

Citations 9

Authors

H Y Hsiao

L C Chiang

P P Ueng

G T Tsao

Affiliations

Soon will be listed here.

Abstract

Four yeasts (Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida utilus, and Rhodotorula toruloides) were tested for their ability to grow and consume D-glucose, D-xylose, D-xylulose, and D-xylitol. Sequential utilization of substrates was observed when D-glucose as mixed with D-xylulose as the carbon source. Catabolite inhibition was tentatively concluded to be responsible for this regulatory mechanism. D-Glucose was also found to inhibit the utilization of D-xylose and D-xylitol in C. utilus and R. toruloides. D-Xylose, D-xylitol, and D-xylulose were consumed simultaneously by R. toruloides and C. utilus.

Citing Articles

Xylose Metabolization by a Strain Isolated in Colombia.

Lagos M, Caviativa J, Pinzon D, Roa D, Basso T, Lozano M Indian J Microbiol. 2023; 63(1):84-90.

PMID: 37179578 PMC: 10172406. DOI: 10.1007/s12088-023-01054-z.

Esophageal mycobiome landscape and interkingdom interactions in esophageal squamous cell carcinoma.

Rao W, Lin Z, Jiang J, Wang J, Lin Z, Fu R Gastroenterol Rep (Oxf). 2023; 11:goad022.

PMID: 37124071 PMC: 10147516. DOI: 10.1093/gastro/goad022.

Valorization of Brewers' Spent Grain for the Production of Lipids by Oleaginous Yeast.

Patel A, Mikes F, Buhler S, Matsakas L Molecules. 2018; 23(12).

PMID: 30469531 PMC: 6320983. DOI: 10.3390/molecules23123052.

Engineering of a xylose metabolic pathway in Rhodococcus strains.

Xiong X, Wang X, Chen S Appl Environ Microbiol. 2012; 78(16):5483-91.

PMID: 22636009 PMC: 3406118. DOI: 10.1128/AEM.08022-11.

Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum.

Hu C, Wu S, Wang Q, Jin G, Shen H, Zhao Z Biotechnol Biofuels. 2011; 4(1):25.

PMID: 21864398 PMC: 3174874. DOI: 10.1186/1754-6834-4-25.

References

Epps H, GALE E . The influence of the presence of glucose during growth on the enzymic activities of Escherichia coli: comparison of the effect with that produced by fermentation acids. Biochem J. 1942; 36(7-9):619-23. PMC: 1266845. DOI: 10.1042/bj0360619. View

Stumm-Zollinger E . Effects of inhibition and repression on the utilization of substrates by heterogeneous bacterial communities. Appl Microbiol. 1966; 14(4):654-64. PMC: 546805. DOI: 10.1128/am.14.4.654-664.1966. View

HOCHSTER R, Watson R . Enzymatic isomerization of D-xylose to D-xylulose. Arch Biochem Biophys. 1954; 48(1):120-9. DOI: 10.1016/0003-9861(54)90313-6. View

Chakravorty M, VEIGA L, BACILA M, HORECKER B . Pentose metabolism in Candida. II. The diphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis. J Biol Chem. 1962; 237:1014-20. View

McGinnis J, Paigen K . Catabolite inhibition: a general phenomenon in the control of carbohydrate utilization. J Bacteriol. 1969; 100(2):902-13. PMC: 250174. DOI: 10.1128/jb.100.2.902-913.1969. View

Russell J, Baldwin R . Substrate preferences in rumen bacteria: evidence of catabolite regulatory mechanisms. Appl Environ Microbiol. 1978; 36(2):319-29. PMC: 291221. DOI: 10.1128/aem.36.2.319-329.1978. View

Wang P, Schneider H . Growth of yeasts on D-xylulose 1. Can J Microbiol. 1980; 26(9):1165-8. DOI: 10.1139/m80-193. View

Gong C, Chen L, Flickinger M, Chiang L, Tsao G . Production of Ethanol from d-Xylose by Using d-Xylose Isomerase and Yeasts. Appl Environ Microbiol. 1981; 41(2):430-6. PMC: 243711. DOI: 10.1128/aem.41.2.430-436.1981. View

Russell J, Baldwin R . Comparison of substrate affinities among several rumen bacteria: a possible determinant of rumen bacterial competition. Appl Environ Microbiol. 1979; 37(3):531-6. PMC: 243250. DOI: 10.1128/aem.37.3.531-536.1979. View

10.

MAGASANIK B . Catabolite repression. Cold Spring Harb Symp Quant Biol. 1961; 26:249-56. DOI: 10.1101/sqb.1961.026.01.031. View

11.

Chiang L, Hsiao H, Ueng P, Tsao G . Enzymatic and Microbial Preparation of d-Xylulose from d-Xylose. Appl Environ Microbiol. 1981; 42(1):66-9. PMC: 243963. DOI: 10.1128/aem.42.1.66-69.1981. View

12.

Wang P, Shopsis C, Schneider H . Fermentation of a pentose by yeasts. Biochem Biophys Res Commun. 1980; 94(1):248-54. DOI: 10.1016/s0006-291x(80)80213-0. View

13.

CIRILLO V . Relationship between sugar structure and competition for the sugar transport system in Bakers' yeast. J Bacteriol. 1968; 95(2):603-11. PMC: 252058. DOI: 10.1128/jb.95.2.603-611.1968. View

14.

McGinnis J, Paigen K . Site of catabolite inhibition of carbohydrate metabolism. J Bacteriol. 1973; 114(2):885-7. PMC: 251854. DOI: 10.1128/jb.114.2.885-887.1973. View

15.

Standing C, Fredrickson A, TSUCHIYA H . Batch- and continuous-culture transients for two substrate systems. Appl Microbiol. 1972; 23(2):354-9. PMC: 380344. DOI: 10.1128/am.23.2.354-359.1972. View