Topo-optical Reactions of the Human Blood Platelet Membrane

Overview

Journal Histochemistry

Specialty Biochemistry

Date 1983 Jan 1

PMID 6196339

Citations 1

Authors

J Makovitzky

S Bozsoky Jr

E Laszlo

Affiliations

Soon will be listed here.

Abstract

The polarization optical analysis of human blood platelets was carried out by means of topo-optical staining reactions. Similar studies have not been performed so far. With this approach we were able to demonstrate the spatially oriented nature of glycoprotein components in the platelet membrane. Using a sialic acid specific topo-optical reaction the sialic acid component of human platelet membrane was selectively demonstrated and the even distribution of sialic acid residues on the membrane surface was also suggested. Polarization optical analysis has shown a membrane-parallel orientation of oligosaccharide chains carrying sialic acids.

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PMID: 2450077 DOI: 10.1007/BF01687364.

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