» Articles » PMID: 6190839

Prospective Study of Gram-stained Stool Smears in Diagnosis of Clostridium Difficile Colitis

Overview
Specialty Microbiology
Date 1983 May 1
PMID 6190839
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Gram stains of stools from patients with diarrhea and control patients with no diarrhea were examined for a predominance of gram-positive rods and the presence of polymorphonuclear leukocytes. Results were compared with those from lower gastrointestinal endoscopy for pseudomembranes. Clostridium difficile culturing, and C. difficile toxin assay. The Gram stain was moderately difficult to interpret and was not useful in diagnosing diarrheal disease associated with C. difficile.

Citing Articles

Culturing and maintaining Clostridium difficile in an anaerobic environment.

Edwards A, Suarez J, McBride S J Vis Exp. 2013; (79):e50787.

PMID: 24084491 PMC: 3871928. DOI: 10.3791/50787.


Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests.

Becker S, Vogt J, Knopp S, Panning M, Warhurst D, Polman K BMC Infect Dis. 2013; 13:37.

PMID: 23347408 PMC: 3579720. DOI: 10.1186/1471-2334-13-37.


Is Fecal Leukocyte Test a good predictor of Clostridium difficile associated diarrhea?.

Reddymasu S, Sheth A, Banks D Ann Clin Microbiol Antimicrob. 2006; 5:9.

PMID: 16623943 PMC: 1459191. DOI: 10.1186/1476-0711-5-9.


Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease.

Sambol S, Merrigan M, Lyerly D, Gerding D, Johnson S Infect Immun. 2000; 68(10):5480-7.

PMID: 10992443 PMC: 101495. DOI: 10.1128/IAI.68.10.5480-5487.2000.


Detection of Clostridium difficile in faeces by direct gas liquid chromatography.

Levett P J Clin Pathol. 1984; 37(2):117-9.

PMID: 6693575 PMC: 498663. DOI: 10.1136/jcp.37.2.117.

References
1.
George W, Sutter V, CITRON D, Finegold S . Selective and differential medium for isolation of Clostridium difficile. J Clin Microbiol. 1979; 9(2):214-9. PMC: 272994. DOI: 10.1128/jcm.9.2.214-219.1979. View

2.
Bartlett J, Chang T, Taylor N, Onderdonk A . Colitis induced by Clostridium difficile. Rev Infect Dis. 1979; 1(2):370-8. DOI: 10.1093/clinids/1.2.370. View

3.
Silva Jr J, FEKETY R . Clostridia and antimicrobial enterocolitis. Annu Rev Med. 1981; 32:327-33. DOI: 10.1146/annurev.me.32.020181.001551. View

4.
Chang T, Bartlett J, Taylor N . Clostridium difficile toxin. Pharmacol Ther. 1981; 13(3):441-52. DOI: 10.1016/0163-7258(81)90025-5. View

5.
George W, Rolfe R, Finegold S . Clostridium difficile and its cytotoxin in feces of patients with antimicrobial agent-associated diarrhea and miscellaneous conditions. J Clin Microbiol. 1982; 15(6):1049-53. PMC: 272251. DOI: 10.1128/jcm.15.6.1049-1053.1982. View