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C-cell Follicles of Canine Thyroid Glands Studied by PAS Reaction and Electron Microscopy

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Journal Cell Tissue Res
Date 1982 Jan 1
PMID 6181891
Citations 2
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Abstract

Small follicles composed solely of C cells were occasionally observed in large C cell groups of dog thyroid glands. The lumina of C-cell follicles were filled with, or contained peripheral depositions of PAS-positive amorphous material, which was similar in ultrastructural features to thyroglobulin-containing colloid in typical thyroid follicles. This indicates that C cells, in addition to secreting calcitonin, produce a glycoprotein that can be stored in the lumina of the follicles.

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