Hoechst 33258 Induced Uncondensed Sites in Marsupial Chromosomes

Overview

Journal Chromosoma

Specialty Molecular Biology

Date 1981 Jan 1

PMID 6168441

Citations 6

Authors

D Hayman

P Sharp

Affiliations

Soon will be listed here.

Abstract

The fluorochrome Hoechst 33258 induces pronounced uncondensed regions at mitosis at one or more specific sites on the X chromosomes of all eighteen species of marsupials belonging to the family Macropodidae which have been examined. The Y chromosomes of nearly all of these species also show sensitive sites. Autosomal regions which respond to this chemical were observed in only five species and there is evidence of polymorphism for two of these. The regions which respond usually show C-banding, but not all C-banding regions are affected. No specific effect was found in the chromosomes of eleven other species examined which are representative of 5 different Australian marsupial families. The implications of the apparent restriction of sex chromosome sensitive sites to macropods are discussed.

Citing Articles

Sex chromosome pairing during male meiosis in marsupials.

Sharp P Chromosoma. 1982; 86(1):27-47.

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Gene mapping in marsupials and monotremes. I. The chromosomes of rodent-marsupial (Macropus) cell hybrids, and gene assignments to the X chromosome of the grey kangaroo.

Dawson G, Graves J Chromosoma. 1984; 91(1):20-7.

PMID: 6525896 DOI: 10.1007/BF00286481.

Heritable fragile sites on human chromosomes. XI. Factors affecting expression of fragile sites at 10q25, 16q22, and 17p12.

Sutherland G, Jacky P, Baker E Am J Hum Genet. 1984; 36(1):110-22.

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Chromosome banding in Amphibia. VIII. An unusual XY/XX-sex chromosome system in Gastrotheca riobambae (Anura, Hylidae).

Schmid M, Haaf T, Geile B, Sims S Chromosoma. 1983; 88(1):69-82.

PMID: 6192977 DOI: 10.1007/BF00329505.

Verification of the structure of the complex sex chromosome system in Lagorchestes conspicillatus Gould (Marsupialia: Mammalia).

Hayman D, Sharp P Chromosoma. 1981; 83(2):263-74.

PMID: 6168442 DOI: 10.1007/BF00286794.

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