Effect of Cholinomimetics on the Release and Uptake of L-[3H] Glutamic Acid in Rat Neostriatum

Overview

Journal Cell Mol Neurobiol

Publisher Springer

Specialties Cell Biology
Molecular Biology
Neurology

Date 1984 Jun 1

PMID 6149020

Citations 1

Authors

O V Godukhin

Budantsev AYu

O V Selifanova

V N Agapova

Affiliations

Soon will be listed here.

Abstract

The effects of cholinomimetics on the release and uptake of L-glutamic acid have been studied by means of local superfusion of rat neostriatum (in vivo) and using striatum slices (in vitro). Cholinomimetics regulate the release of L-glutamic acid through both muscarinic (m-) and nicotinic (n-) choline receptors according to the mechanism of negative feedback. Cholinomimetics regulate release through presynaptic receptors. The effect of n-cholinomimetics is mediated by neostriatum interneurons.

Citing Articles

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Exposito I, Sanz B, Mora F Neurochem Res. 1997; 22(12):1485-90.

PMID: 9357014 DOI: 10.1023/a:1021906529055.

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