Aetiology of Parkinson's Disease

Overview

Journal Lancet

Publisher Elsevier

Specialty General Medicine

Date 1983 Dec 24

PMID 6140548

Citations 81

Authors

D B Calne

J W Langston

Affiliations

Soon will be listed here.

Abstract

It is suggested here that in most cases of Parkinson's disease the cause may be an environmental factor, possibly toxic, superimposed on a background of slow, sustained neuronal loss due to advancing age.

Citing Articles

Modulation of Autophagy and Nitric Oxide Signaling via Glycyrrhizic Acid and 7-Nitroindazole in MPTP-induced Parkinson's Disease Model.

Kartik S, Pal R, Chaudhary M, Nath R, Kumar M Ann Neurosci. 2025; 31(4):265-276.

PMID: 39840143 PMC: 11744622. DOI: 10.1177/09727531231191661.

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders.

Norouzkhani N, Karimi A, Badami N, Jalalifar E, Mahmoudvand B, Ansari A Front Pharmacol. 2022; 13:960037.

PMID: 36438833 PMC: 9685814. DOI: 10.3389/fphar.2022.960037.

4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation.

Tiwari S, Gupta P, Singh A, Chaturvedi S, Wahajuddin M, Mishra A Neurochem Res. 2022; 47(11):3385-3401.

PMID: 35922743 DOI: 10.1007/s11064-022-03691-0.

Case Report: Synucleinopathy Associated With Neurotoxicity in Sheep.

Tayebi M, Pinczowski P, Habiba U, Khan R, David M, Summers B Front Vet Sci. 2021; 8:736567.

PMID: 34722702 PMC: 8551671. DOI: 10.3389/fvets.2021.736567.

A critical role for GM1 ganglioside in the pathophysiology and potential treatment of Parkinson's disease.

Schneider J Glycoconj J. 2021; 39(1):13-26.

PMID: 34037912 DOI: 10.1007/s10719-021-10002-2.