Morphological Evidence for Identifying the Viruses of Hemorrhagic Fever with Renal Syndrome As Candidate Members of the Bunyaviridae Family. Brief Report
Overview
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Thin section immuno-electron microscopy has been successfully applied to investigate and identify the classical and mild form of HFRS viruses isolated in the People's Republic of China. The results showed that all the 8 strains studied (derived from different parts of China, adapted in different cell lines) share a common morphology and morphogenesis. Essentially, the viruses possess characteristics of members of the Bunyaviridae Family, however, differing by a larger size and size variation and formation of cytoplasmic viral inclusions.
Hantavirus entry: Perspectives and recent advances.
Mittler E, Dieterle M, Kleinfelter L, Slough M, Chandran K, Jangra R Adv Virus Res. 2019; 104:185-224.
PMID: 31439149 PMC: 6881143. DOI: 10.1016/bs.aivir.2019.07.002.
Genetic characterization of a hantavirus isolated from Heilongjiang province, China.
Wang Y, Cao S, Cheng C, Ju W, Hua Y Can J Vet Res. 2019; 83(1):75-77.
PMID: 30670905 PMC: 6318823.
Slough M, Chandran K, Jangra R mBio. 2019; 10(1).
PMID: 30622188 PMC: 6325249. DOI: 10.1128/mBio.02372-18.
Cao S, Ma J, Cheng C, Ju W, Wang Y BMC Vet Res. 2016; 12:69.
PMID: 27038799 PMC: 4818876. DOI: 10.1186/s12917-016-0695-7.
Morphologic differentiation of viruses beyond the family level.
Goldsmith C Viruses. 2014; 6(12):4902-13.
PMID: 25502324 PMC: 4276935. DOI: 10.3390/v6124902.