Intestinal Lavage in the Treatment of Crohn's Disease: a Pilot Study

Overview

Journal Klin Wochenschr

Specialty General Medicine

Date 1982 Apr 1

PMID 6122755

Citations 1

Authors

W Wellmann

F W Schmidt

Affiliations

Soon will be listed here.

Abstract

Taking into account that a damaged mucosal barrier may be responsible for the impairment and some systemic complications in Crohn's disease, we employed intestinal lavage as a therapeutic method in six patients suffering from active Crohn's disease. The results were compared with those obtained from a control group that received similar treatment with the exception of the lavage. Intestinal lavage was carried out with 18 1 of normal saline administered via a jejunal tube over a period of 2 h. The lavage procedure was tolerated well by all patients. A significant decrease of the Crohn's disease activity index and a significantly lower hospitalization time suggest a benefit in using the lavage method. Provided that these results can be confirmed in a larger series of patients, intestinal lavage may contribute to the strategy of conservative treatment of Crohn's disease.

Citing Articles

Endotoxaemia in active Crohn's disease. Treatment with whole gut irrigation and 5-aminosalicylic acid.

Wellmann W, Fink P, Benner F, Schmidt F Gut. 1986; 27(7):814-20.

PMID: 3732891 PMC: 1433583. DOI: 10.1136/gut.27.7.814.

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