Crystallization of Intrinsic Membrane Proteins
Overview
Overview
Journal
J Bioenerg Biomembr
Publisher
Springer
Specialties
Biochemistry
Biology
Endocrinology
Biology
Endocrinology
Date
1984 Dec 1
PMID
6100372
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
After many years of discouraging failures, it is now possible to crystallize the intrinsic membrane proteins and to obtain structural information from diffraction studies on the crystals. The strategy for the crystallization consists of depletion of boundary phospholipids from the protein and complex formation with specific ligands.
References
1.
Seki S, Oda T
. Studies on cytochrome oxidase. II. Ultrastructure of cytochrome oxidase. Arch Biochem Biophys. 1970; 138(1):122-34.
DOI: 10.1016/0003-9861(70)90291-2.
View
2.
Yagi K, Ozawa T
. CRYSTALLIZATION OF A HOLO-ENZYME-PRODUCT COMPLEX OF D-AMINOACID OXIDASE. J Biochem. 1963; 54:204-5.
View
3.
Green D, Perdue J
. Membranes as expressions of repeating units. Proc Natl Acad Sci U S A. 1966; 55(5):1295-302.
PMC: 224315.
DOI: 10.1073/pnas.55.5.1295.
View
4.
HATEFI Y, HAAVIK A, FOWLER L, Griffiths D
. Studies on the electron transfer system. XLII. Reconstitution of the electron transfer system. J Biol Chem. 1962; 237:2661-9.
View
5.
Michel H, Oesterhelt D
. Three-dimensional crystals of membrane proteins: bacteriorhodopsin. Proc Natl Acad Sci U S A. 1980; 77(3):1283-5.
PMC: 348478.
DOI: 10.1073/pnas.77.3.1283.
View