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A Mus Dunni Cell Line That Lacks Sequences Closely Related to Endogenous Murine Leukemia Viruses and Can Be Infected by Ectropic, Amphotropic, Xenotropic, and Mink Cell Focus-forming Viruses

Overview
Journal J Virol
Date 1984 Nov 1
PMID 6092693
Citations 139
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Abstract

A Mus dunni cell line has been developed that is permissive for all four classes of murine leukemia viruses (MuLV): ecotropic, amphotropic, xenotropic, and mink cell focus-forming viruses. The M. dunni cells contain fewer MuLV-related sequences than do feral or domestic mouse, rat, or mink cells. Infection of the line by ecotropic MuLV induces a distinct cytopathic effect, and the cells can be readily transfected by MuLV DNA. The M. dunni line has been used to isolate an endogenous MuLV from the SC-1 feral mouse cell line.

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